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Quantitative CEST with BIRDS

D. Coman, G. Kiefer, D. L. Rothman, D. A. Sherry, and F. Hyder Diagnostic Radiology, Yale University, New Haven, CT, United States, Quantitative Neuroscience with Magnetic Resonance (QNMR), Yale University, New Haven, CT, United States, Macrocyclics, Dallas, TX, United States, Diagnostic Radiology and Biomedical Engineering, Yale University, New Haven, CT, United States, Advanced Imaging Resear...

Cest / Wiener Neustadt Bioelectrochemistry and More

Pressure Dependent Signal Enhancement in Hyper-CEST

Introduction The so called hyper-CEST method promises tremendous potential on molecule-specific MR imaging using hyperpolarized Xe caged in functionalized cryptophane cages [1]. It was shown that these biosensors can be utilized as highly sensitive temperature probes [2] and that molecule-specific signals in the lower nM regime can be detected when experimental parameters are optimized to yield...

Simulation and visualization of the Saint-Venant system using GPUs

We consider three high-resolution schemes for computing shallow-water waves as described by the Saint-Venant system and discuss how to develop highly efficient implementations using graphical processing units (GPUs). The schemes are well-balanced for lake-at-rest problems, handle dry states, and support linear friction models. The first two schemes handle dry states by switching variables in th...

Intrinsic nonlinear models of shells for Saint Venant-Kirchhoff materials

The first complete linear theory, based on Kirchhoff’s [1850] earlier works on plates, was given by Love [1888]. The modern theory (linear and nonlinear) comes from the works by Naghdi and Koiter in the sixties. In such models the displacement variables are functions defined on the mean surface and the resulting equations are differential equations on a smooth 2-dimensional submanifold of the t...